Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084295 | 0.96 | RARB (0.38) | HTR2AHTR2CHTR1BHTR2BRARB | |
| SCHEMBL17084292 | 0.96 | RARB (0.38) | HTR2AHTR2CHTR1BHTR2BRARB | |
| SCHEMBL17898353 | 0.96 | HRH3 (0.36) | HRH3HPGD | |
| SCHEMBL17084299 | 0.96 | RARB (0.38) | HTR2AHTR2CHTR1BHTR2BRARB | |
| SCHEMBL17086819 | 0.94 | HTR2A (0.41) | HTR2AHTR2CHTR1BHTR2BRARB | |
| SCHEMBL17086824 | 0.94 | HTR2A (0.41) | HTR2AHTR2CHTR1BHTR2BRARB | |
| SCHEMBL17898351 | 0.93 | HRH3 (0.34) | HRH3HPGDCHRM2CHRM4CHRM5 | |
| SCHEMBL17898350 | 0.93 | HPGD (0.35) | HTR2AHTR2CHTR1BHTR2BHRH3 | |
| SCHEMBL17897394 | 0.92 | HPGD (0.40) | HTR2AHTR2CHTR1BHTR2BRARB | |
| SCHEMBL17897395 | 0.92 | CHRM2 (0.36) | HTR2AHTR2CHTR1BHTR2BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194561-A1 | DIFLUOROPHENYL LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2016-07-07 | — | — | US | disclosed |