Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897396 | 0.96 | HTR2A (0.37) | HRH3HPGD | |
| SCHEMBL17898351 | 0.95 | HRH3 (0.34) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17898352 | 0.95 | HPGD (0.41) | HRH3GPR119HPGD | |
| SCHEMBL17898349 | 0.91 | HRH3 (0.34) | HRH3KDM4ERECQLTDP1HRH2 | |
| SCHEMBL17084295 | 0.91 | RARB (0.38) | — | |
| SCHEMBL17084292 | 0.91 | RARB (0.38) | — | |
| SCHEMBL17084299 | 0.91 | RARB (0.38) | — | |
| SCHEMBL17898350 | 0.90 | HPGD (0.35) | HRH3HRH2HRH1HPGD | |
| SCHEMBL17086819 | 0.89 | HTR2A (0.41) | HRH3HPGD | |
| SCHEMBL17086824 | 0.89 | HTR2A (0.41) | HRH3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194561-A1 | DIFLUOROPHENYL LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2016-07-07 | — | — | US | disclosed |