SCHEMBL17897397

SCHEMBL17897397

CCCCCC1CCC(c2ccc(-c3ccc(OCCCC4CCC(CCC)CC4)cc3)c(F)c2F)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
CYP2D6 P10635 4/20 0.34
CYP3A4 P08684 2/20 0.34
CYP1A2 P05177 3/20 0.33
CYP19A1 P11511 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
RAB9A P51151 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RARB P10826 4/20 0.33
RARA P10276 1/20 0.33
PTPN11 Q06124 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17084295 0.94 RARB (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17084292 0.94 RARB (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17897362 0.94 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17084299 0.94 RARB (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17897398 0.94 CHRM2 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17898349 0.93 HRH3 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17897395 0.93 CHRM2 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17897396 0.91 HTR2A (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17897394 0.91 HPGD (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL15581217 0.89 ALOX5AP (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160194561-A1 DIFLUOROPHENYL LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2016-07-07 US disclosed