Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897466 | 1.00 | HTT (0.40) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL17897432 | 0.96 | PTGER4 (0.39) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL17897442 | 0.96 | CYP2C9 (0.38) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL22519635 | 0.96 | NLRP3 (0.37) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL24241377 | 0.95 | PTGER4 (0.39) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL17897435 | 0.95 | PTGER4 (0.39) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL17897446 | 0.95 | CYP2C9 (0.38) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL18679375 | 0.94 | MEN1 (0.43) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL18679360 | 0.94 | MEN1 (0.43) | HTTCYP2C9SIRT2SIRT1KDM4E | |
| SCHEMBL18679363 | 0.94 | MEN1 (0.43) | HTTCYP2C9SIRT2SIRT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160197286-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |
| US-20160197286-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |