Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15778541 | 0.95 | AKT1 (0.73) | AKT1ALDH1A1CYP1A2ALOX12NPSR1 | |
| SCHEMBL351989 | 0.89 | AKT1 (1.00) | AKT1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL17897769 | 0.87 | AKT1 (0.77) | AKT1ALDH1A1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL17897745 | 0.83 | AKT1 (0.82) | AKT1ALDH1A1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL15778482 | 0.80 | AKT1 (0.63) | AKT1ALDH1A1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL351879 | 0.79 | AKT1 (1.00) | AKT1ALDH1A1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL15778845 | 0.78 | AKT1 (0.81) | AKT1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL17897746 | 0.77 | AKT1 (0.64) | AKT1ALDH1A1CYP1A2LMNAMAPT | |
| SCHEMBL17897754 | 0.77 | AKT1 (0.61) | AKT1ALDH1A1CYP1A2LMNAMAPT | |
| SCHEMBL352146 | 0.76 | AKT1 (1.00) | AKT1ALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | TRRAP, NAT1, AHR | AKT1 2603/4885ALDH1A1 445/4885CYP1A2 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.