Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897746 | 0.97 | AKT1 (0.64) | AKT1GAAALDH1A1CYP1A2MAPT | |
| SCHEMBL15788816 | 0.90 | GAA (0.62) | AKT1GAAALDH1A1CYP1A2ALOX12 | |
| SCHEMBL25795128 | 0.85 | AKT1 (0.50) | AKT1GAAMAPTNPSR1CES2 | |
| SCHEMBL17897769 | 0.83 | AKT1 (0.77) | AKT1GAAALDH1A1CYP1A2MAPT | |
| SCHEMBL17897751 | 0.81 | AKT1 (0.71) | AKT1GAAALDH1A1CYP1A2MAPT | |
| SCHEMBL17897762 | 0.81 | AKT1 (0.79) | AKT1GAAALDH1A1CYP1A2MAPT | |
| SCHEMBL17897767 | 0.81 | AKT1 (0.68) | AKT1GAAALDH1A1CYP1A2MAPT | |
| SCHEMBL17897765 | 0.81 | AKT1 (0.91) | AKT1GAAALDH1A1CYP1A2MAPT | |
| SCHEMBL8768316 | 0.80 | GAA (0.48) | AKT1GAAALDH1A1CYP1A2MAPT | |
| SCHEMBL1004777 | 0.79 | CES2 (0.59) | GAAMAPTNPSR1CES2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | TRRAP, NAT1, AHR | AKT1 2603/4885GAA 2805/4885ALDH1A1 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.