Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.57 |
| ▸ | CYTH3 | O43739 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15777239 | 0.90 | AKT1 (0.65) | AKT1PDPK1CYTH3ALDH1A1MAPT | |
| SCHEMBL17897744 | 0.87 | AKT1 (0.65) | AKT1PDPK1CYTH3ALDH1A1MAPT | |
| SCHEMBL28437427 | 0.80 | PDPK1 (0.55) | AKT1PDPK1CYTH3ALDH1A1MAPT | |
| SCHEMBL15777646 | 0.79 | PDPK1 (0.77) | AKT1PDPK1CYTH3ALDH1A1MAPT | |
| SCHEMBL17897770 | 0.78 | AKT1 (0.58) | AKT1PDPK1CYTH3ALDH1A1MAPT | |
| SCHEMBL17897743 | 0.77 | AKT1 (0.64) | AKT1PDPK1CYTH3ALDH1A1MAPT | |
| SCHEMBL17891681 | 0.77 | AKT1 (0.60) | AKT1PDPK1CYTH3ALDH1A1MAPT | |
| SCHEMBL2972082 | 0.76 | SLC9A1 (0.60) | ALDH1A1MAPTRAB9AHPGDNPC1 | |
| SCHEMBL1455497 | 0.74 | POLB (0.60) | ALDH1A1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL15777209 | 0.73 | AKT1 (0.83) | AKT1PDPK1CYTH3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | TRRAP, NAT1, AHR | AKT1 2603/4885PDPK1 4430/4885CYTH3 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.