Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898818 | 0.95 | RIPK1 (0.32) | RIPK1ABCB1 | |
| SCHEMBL15366614 | 0.94 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL16062585 | 0.94 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL16605283 | 0.92 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL17898667 | 0.92 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL17427098 | 0.91 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL19628450 | 0.90 | — | — | |
| SCHEMBL17898878 | 0.89 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL15373266 | 0.89 | ABCB1 (0.31) | ABCB1CTSLCTSSCTSK | |
| SCHEMBL17898670 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |