Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16605375 | 0.91 | GAA (0.35) | GAANAAAKMT2AF2F10 | |
| SCHEMBL16604075 | 0.91 | GAA (0.35) | GAANAAAKMT2AF2F10 | |
| SCHEMBL16604076 | 0.91 | GAA (0.35) | GAANAAAKMT2AF2F10 | |
| SCHEMBL16605410 | 0.90 | GAA (0.36) | GAANAAAKMT2ACTSDF2 | |
| SCHEMBL16605406 | 0.89 | GAA (0.34) | GAANAAAF2F10PRSS1 | |
| SCHEMBL16605400 | 0.88 | GAA (0.33) | GAANAAAF2F10PRSS1 | |
| SCHEMBL17898872 | 0.87 | NAAA (0.36) | GAANAAAALDH1A1KMT2ACTSD | |
| SCHEMBL17898729 | 0.86 | GAA (0.34) | GAANAAAALDH1A1KMT2AF2 | |
| SCHEMBL17898867 | 0.86 | GAA (0.34) | GAANAAAALDH1A1KMT2ACTSD | |
| SCHEMBL17898731 | 0.83 | GAA (0.39) | GAANAAAALDH1A1KMT2ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |