Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10409847 | 0.82 | KDM3A (0.50) | — | |
| Hydrochloric Acid SCHEMBL10772341 | 0.82 | KDM3A (0.50) | — | |
| Hydrochloric Acid SCHEMBL6939511 | 0.82 | KDM3A (0.50) | — | |
| Hydrochloric Acid SCHEMBL8845531 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8855133 | 0.82 | KDM3A (0.50) | — | |
| Hydrochloric Acid SCHEMBL11058934 | 0.82 | KDM3A (0.50) | — | |
| SCHEMBL44148 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL24279 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL10408499 | 0.82 | KDM3A (0.50) | — | |
| SCHEMBL9648838 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937092-B2 | Aryl or N-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands | GRUENENTHAL GMBH (DE) | 2015-01-20 | — | — | US | disclosed |
| US-8765733-B2 | Amine substituted methanesulfonamide derivatives as vanilloid receptor ligands | GRUENENTHAL GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-8741801-B2 | Catalytic platinum and its 3d-transition-metal alloy nanoparticles | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130079320-A1 | Amine Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2013-03-28 | — | — | US | disclosed |
| US-20130079377-A1 | Aryl or N-heteroaryl Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2013-03-28 | — | — | US | disclosed |
| US-20130079373-A1 | Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2013-03-28 | — | — | US | disclosed |
| US-20110124499-A1 | CATALYTIC PLATINUM AND ITS 3d-TRANSITION-METAL ALLOY NANOPARTICLES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-05-26 | — | — | US | disclosed |
| US-6174512-B1 | HEATING A LIQUID MIXTURE CONTAINING A TETRAALKYL ORTHOSILICATE, A LINEAR ALKYLAMINE, AN INORGANIC ACID AND WATER, DRYING TO FORM A CATALYST FOR ADSORBING, SEPARATING, STORING OR DECOMPOSITING THE GAS OR IONS | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2001-01-16 | — | — | US | disclosed |
| US-5911944-A | OPTOELECTRONIC MODULATOR, METAL OXIDE, SOL-GEL TECHNIQUE | MINOLTA CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |