Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CCR3 | P51677 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16605381 | 0.89 | SCN9A (0.37) | SCN9AGAAKDM4D | |
| SCHEMBL17899061 | 0.86 | SCN9A (0.36) | SCN9AGAAKDM4D | |
| SCHEMBL17899062 | 0.86 | SCN9A (0.36) | SCN9AGAA | |
| SCHEMBL17427144 | 0.84 | GAA (0.40) | SCN9AGAAKDM4D | |
| SCHEMBL16864965 | 0.84 | GAA (0.35) | SCN9AGAAKDM4D | |
| SCHEMBL20169788 | 0.84 | GAA (0.35) | SCN9AGAAKDM4D | |
| SCHEMBL16603880 | 0.83 | SCN9A (0.36) | SCN9AGAAKDM4D | |
| SCHEMBL16605402 | 0.82 | KMT2A (0.33) | GAA | |
| SCHEMBL17903383 | 0.81 | KMT2A (0.37) | SCN9AGAA | |
| SCHEMBL16605397 | 0.81 | KMT2A (0.41) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |