Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899060 | 0.86 | SCN9A (0.35) | SCN9AKDM4DGAA | |
| SCHEMBL17899062 | 0.86 | SCN9A (0.36) | SCN9AGAA | |
| SCHEMBL15366872 | 0.85 | KMT2A (0.38) | GAA | |
| SCHEMBL15366868 | 0.85 | KMT2A (0.38) | GAA | |
| SCHEMBL15531266 | 0.85 | KMT2A (0.38) | GAA | |
| SCHEMBL15366865 | 0.85 | KMT2A (0.38) | GAA | |
| SCHEMBL15364406 | 0.85 | SCN9A (0.36) | SCN9AKDM4DGAA | |
| SCHEMBL15364412 | 0.85 | SCN9A (0.36) | SCN9AKDM4DGAA | |
| SCHEMBL19614773 | 0.84 | SCN9A (0.35) | SCN9AKDM4D | |
| SCHEMBL19614775 | 0.84 | SCN9A (0.35) | SCN9AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |