SCHEMBL17899189

SCHEMBL17899189

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5ccc(-c6cccc7c6oc6ccccc67)cc5)cc4)nc(-c4ccccc4)n3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.53
MAPT P10636 7/20 0.45
ALDH1A1 P00352 5/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
HPGD P15428 4/20 0.45
NTSR1 P30989 1/20 0.45
KDM4E B2RXH2 4/20 0.43
LMNA P02545 3/20 0.43
GLA P06280 1/20 0.43
GGPS1 O95749 1/20 0.43
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
PRKDC P78527 2/20 0.40
PTGES2 Q9H7Z7 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9881126 1.00 ALOX5 (0.53) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL9881120 1.00 ALOX5 (0.53) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL17879060 1.00 ALOX5 (0.53) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL15501947 1.00 ALOX5 (0.53) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL19885523 0.99 ALOX5 (0.55) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL15501640 0.99 ALOX5 (0.55) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL12996524 0.99 ALOX5 (0.55) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL19397381 0.96 ALOX5 (0.55) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL15501597 0.96 ALOX5 (0.57) ALOX5MAPTALDH1A1MEN1KMT2A
SCHEMBL15501712 0.95 ALOX5 (0.49) ALOX5MAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed