SCHEMBL17899294

SCHEMBL17899294

c1ccc2c(c1)cc(-c1ccc3cc(-c4ccc(-c5ccc6ccc7cccnc7c6n5)cc4)ccc3c1)c1ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.48
CCR1 P32246 5/20 0.42
CCR8 P51685 5/20 0.42
CCR5 P51681 3/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GMNN O75496 1/20 0.42
TP53 P04637 1/20 0.42
HSP90AA1 P07900 1/20 0.42
MMP2 P08253 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
MMP9 P14780 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
MMP8 P22894 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899293 0.93 CYP11B1 (0.51) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL17899298 0.92 CYP11B1 (0.49) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL23370571 0.92 CYP11B1 (0.53) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL17899304 0.91 CYP11B1 (0.48) CYP11B1KDM4ETP53MAPTHIF1A
SCHEMBL24030160 0.90 CYP11B1 (0.46) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL24454210 0.89 CYP11B1 (0.45) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL17899297 0.88 CYP11B1 (0.50) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL20363802 0.87 SMN1; SMN2 (0.52) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL18902518 0.86 CCR1 (0.47) CYP11B1CCR1CCR8CCR5LMNA
SCHEMBL17899299 0.86 CCR1 (0.47) CYP11B1CCR1CCR8CCR5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552259-B1 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20220393113-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed