SCHEMBL17899298

SCHEMBL17899298

c1cc(-c2ccc3cc(-c4cc5ccccc5c5ccccc45)ccc3c2)cc(-c2ccc3ccc4cccnc4c3n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.49
CYP17A1 P05093 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP11B2 P19099 1/20 0.41
LMNA P02545 2/20 0.40
CCR1 P32246 2/20 0.40
CCR8 P51685 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GMNN O75496 1/20 0.40
TP53 P04637 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MMP2 P08253 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
MMP9 P14780 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
NFKB1 P19838 1/20 0.40
MMP8 P22894 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899297 0.94 CYP11B1 (0.50) CYP11B1CYP17A1CYP19A1CYP11B2LMNA
SCHEMBL17899294 0.92 CYP11B1 (0.48) CYP11B1CYP17A1CYP19A1CYP11B2LMNA
SCHEMBL25850589 0.91 CCR1 (0.43) CYP11B1CYP17A1CYP19A1CYP11B2LMNA
SCHEMBL24030160 0.90 CYP11B1 (0.46) CYP11B1CYP17A1CYP19A1CYP11B2LMNA
SCHEMBL24454210 0.89 CYP11B1 (0.45) CYP11B1LMNACCR1CCR8KDM4E
SCHEMBL24781651 0.88 CYP11B1 (0.46) CYP11B1CYP17A1CYP19A1CYP11B2KDM4E
SCHEMBL17899302 0.88 CYP11B1 (0.46) CYP11B1CYP17A1CYP19A1CYP11B2KDM4E
SCHEMBL19768312 0.88 CYP11B1 (0.45) CYP11B1LMNACYP3A4HTTBRD4
SCHEMBL21851279 0.87 CYP11B1 (0.51) CYP11B1LMNACCR1CCR8KDM4E
SCHEMBL13706113 0.87 TOP1 (0.43) CYP11B1CYP17A1CYP19A1CYP11B2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123637-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-20 US disclosed
US-11552259-B1 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed