Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | CDK8 | P49336 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899317 | 0.98 | KDM4E (0.53) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL18806866 | 0.98 | KDM4E (0.55) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL29314792 | 0.97 | KDM4E (0.51) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL29314796 | 0.97 | KDM4E (0.51) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL26364628 | 0.97 | KDM4E (0.50) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL25850634 | 0.95 | KDM4E (0.51) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL29250321 | 0.92 | KDM4E (0.54) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL14900765 | 0.89 | KDM4E (0.47) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL17899318 | 0.88 | KDM4E (0.66) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL17899320 | 0.88 | KDM4E (0.48) | KDM4EPARP1AXLCDK8CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160197289-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |
| US-20160197289-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |