Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25850634 | 0.89 | KDM4E (0.51) | KDM4EPARP1CYP11B1CYP11B2BIRC5 | |
| SCHEMBL26364628 | 0.88 | KDM4E (0.50) | KDM4EPARP1CYP11B1CYP11B2BIRC5 | |
| SCHEMBL17899321 | 0.88 | KDM4E (0.54) | KDM4EPARP1CYP11B1CYP11B2BIRC5 | |
| SCHEMBL17899317 | 0.87 | KDM4E (0.53) | KDM4EPARP1CYP11B1CYP11B2BIRC5 | |
| SCHEMBL18806866 | 0.86 | KDM4E (0.55) | KDM4EPARP1CYP11B1CYP11B2EGLN3 | |
| SCHEMBL17899322 | 0.86 | KDM4E (0.46) | KDM4EPARP1CYP11B1CYP11B2BIRC5 | |
| SCHEMBL29314792 | 0.85 | KDM4E (0.51) | KDM4EPARP1CYP11B1CYP11B2BIRC5 | |
| SCHEMBL29314796 | 0.85 | KDM4E (0.51) | KDM4EPARP1CYP11B1CYP11B2BIRC5 | |
| SCHEMBL14900765 | 0.83 | KDM4E (0.47) | KDM4EPARP1CYP11B1CYP11B2EGLN3 | |
| SCHEMBL25850570 | 0.83 | KDM4E (0.44) | KDM4EPARP1BIRC5ACVR1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160197289-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |
| US-20160197289-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |