SCHEMBL17899322

SCHEMBL17899322

c1cc(-c2cnc3c(ccc4ccc(-c5cccc6ccccc56)nc43)c2)cc(-c2cnc3c(ccc4ccc(-c5cccc6ccccc56)nc43)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
PARP1 P09874 2/20 0.41
NOS1 P29475 1/20 0.39
BIRC5 O15392 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
CCNT1 O60563 1/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
CDK9 P50750 1/20 0.38
ATR Q13535 1/20 0.38
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
RAB9A P51151 1/20 0.36
BMPR1B O00238 1/20 0.36
ACVRL1 P37023 1/20 0.36
ACVR1 Q04771 1/20 0.36
PIM1 P11309 1/20 0.36
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850570 0.89 KDM4E (0.44) KDM4EPARP1NOS1BIRC5ALDH1A1
SCHEMBL10032316 0.87 AR (0.42) KDM4EPARP1NOS1ALDH1A1HPGD
SCHEMBL10032412 0.87 AR (0.42) KDM4EPARP1NOS1ALDH1A1HPGD
SCHEMBL17899320 0.86 KDM4E (0.48) KDM4EPARP1BIRC5ACVR1PIM1
SCHEMBL10032286 0.85 AR (0.43) KDM4EPARP1NOS1ALDH1A1HPGD
SCHEMBL10032382 0.84 CA12 (0.43) KDM4EPARP1ALDH1A1HPGDMAPT
SCHEMBL10032414 0.84 CA12 (0.43) KDM4EPARP1ALDH1A1HPGDMAPT
SCHEMBL10032310 0.84 CA12 (0.43) KDM4EPARP1ALDH1A1HPGDMAPT
SCHEMBL25850634 0.84 KDM4E (0.51) KDM4EPARP1BIRC5RAB9APIM1
SCHEMBL10032342 0.82 AR (0.41) KDM4EPARP1NOS1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed