Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316511 | 0.91 | KDM4E (0.65) | KDM4EPARP1ESR1ESR2AXL | |
| SCHEMBL1073348 | 0.89 | KDM4E (0.67) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL30238107 | 0.89 | KDM4E (0.67) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL17899318 | 0.87 | KDM4E (0.66) | KDM4EPARP1ESR1ESR2AXL | |
| SCHEMBL28421700 | 0.87 | KDM4E (0.65) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL30238011 | 0.87 | KDM4E (0.65) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL25850668 | 0.86 | KDM4E (0.56) | KDM4EPARP1AXLCDK8CYP11B1 | |
| SCHEMBL22909967 | 0.84 | KDM4E (0.57) | KDM4EPARP1ESR2AXLCDK8 | |
| SCHEMBL2724557 | 0.82 | ESR1 (0.58) | ESR1ESR2BACE1FGFR1HSD17B1 | |
| SCHEMBL30703158 | 0.82 | ESR1 (0.58) | ESR1ESR2BACE1FGFR1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160197289-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |
| US-20160197289-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-07 | — | — | US | disclosed |