SCHEMBL25850668

SCHEMBL25850668

c1ccc(-c2cnc3c(ccc4cc(-c5ccc(-c6ccc(-c7ccccc7)c7ccccc67)cc5)cnc43)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
PARP1 P09874 1/20 0.49
AXL P30530 3/20 0.46
CDK8 P49336 2/20 0.46
TNIK Q9UKE5 1/20 0.46
MAP4K4 O95819 3/20 0.45
USP7 Q93009 1/20 0.45
ACVR1 Q04771 1/20 0.44
EGLN3 Q9H6Z9 1/20 0.44
TYK2 P29597 1/20 0.43
MINK1 Q8N4C8 1/20 0.43
SRPK1 Q96SB4 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
MAPK10 P53779 1/20 0.43
PSMB5 P28074 1/20 0.42
MAP3K11 Q16584 1/20 0.42
PDGFRB P09619 1/20 0.41
PDGFRA P16234 1/20 0.41
CHEK2 O96017 1/20 0.41
MKNK1 Q9BUB5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31316511 0.91 KDM4E (0.65) KDM4EPARP1AXLCDK8TNIK
SCHEMBL30238107 0.89 KDM4E (0.67) KDM4EPARP1AXLCDK8TNIK
SCHEMBL1073348 0.89 KDM4E (0.67) KDM4EPARP1AXLCDK8TNIK
SCHEMBL28421700 0.87 KDM4E (0.65) KDM4EPARP1AXLCDK8TNIK
SCHEMBL30238011 0.87 KDM4E (0.65) KDM4EPARP1AXLCDK8TNIK
SCHEMBL17899326 0.86 KDM4E (0.56) KDM4EPARP1AXLCDK8TNIK
SCHEMBL13706268 0.84 KDM4E (0.58) KDM4EPARP1AXLCDK8TNIK
SCHEMBL20713579 0.84 KDM4E (0.45) KDM4EPARP1MAP4K4CLK4MAPK10
SCHEMBL22909967 0.84 KDM4E (0.57) KDM4EPARP1AXLCDK8MAP4K4
SCHEMBL13019223 0.84 KDM4E (0.62) KDM4EPARP1AXLCDK8TNIK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711972-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed
US-11711972-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11711972-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof PPOX, ESR1, CCNE2 KDM4E 1749/4885PARP1 1212/4885AXL 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.