Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850101 | 0.86 | USP30 (0.34) | USP30RECQLEPHX1HPGDUSP2 | |
| SCHEMBL23853479 | 0.86 | USP30 (0.34) | USP30RECQLEPHX1HPGDUSP2 | |
| SCHEMBL17902765 | 0.83 | RORC (0.30) | — | |
| SCHEMBL894193 | 0.82 | USP30 (0.37) | USP30RECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL19055985 | 0.82 | USP30 (0.37) | USP30RECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL17902789 | 0.81 | — | — | |
| SCHEMBL18323857 | 0.79 | BTK (0.33) | — | |
| SCHEMBL21564458 | 0.76 | RECQL (0.45) | USP30RECQLEPHX1HPGDUSP2 | |
| SCHEMBL23352908 | 0.73 | RECQL (0.46) | USP30RECQLEPHX1HPGDKDM4E | |
| SCHEMBL21564475 | 0.72 | RECQL (0.46) | USP30RECQLEPHX1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016108707-A1 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-07-07 | — | — | WO | disclosed |