Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18969703 | 0.90 | KDM4E (0.47) | KDM4EATML3MBTL1HDAC6RORC | |
| SCHEMBL11379057 | 0.90 | KDM4E (0.61) | KDM4EATML3MBTL1RORCPLA2G2A | |
| SCHEMBL17906201 | 0.87 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC6RORC | |
| SCHEMBL2758580 | 0.87 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC6RORC | |
| SCHEMBL11986606 | 0.86 | KDM4E (0.48) | KDM4EATML3MBTL1GPR3HDAC6 | |
| SCHEMBL12757623 | 0.85 | KDM4E (0.52) | KDM4EATML3MBTL1GPR3HDAC6 | |
| SCHEMBL17367768 | 0.84 | KDM4E (0.60) | KDM4EATML3MBTL1RORCPLA2G2A | |
| SCHEMBL22454015 | 0.84 | KDM4E (0.41) | KDM4EATML3MBTL1HDAC6RORC | |
| SCHEMBL7140707 | 0.84 | MAPT (0.54) | KDM4EATML3MBTL1ALDH1A1POLB | |
| SCHEMBL10021229 | 0.84 | KDM4E (0.50) | KDM4EATML3MBTL1GPR3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9966537-B2 | Compositions with 2,3-disubstituted indoles as charge transport materials, and display devices fabricated therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-08 | — | — | US | disclosed |
| US-9966537-B2 | Compositions with 2,3-disubstituted indoles as charge transport materials, and display devices fabricated therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-08 | — | — | US | disclosed |
| US-9966537-B2 | Compositions with 2,3-disubstituted indoles as charge transport materials, and display devices fabricated therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170373253-A1 | Compositions with 2,3-Disubstituted Indoles as Charge Transport Materials, and Display Devices Fabricated Therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2017-12-28 | — | — | US | disclosed |
| US-20170373253-A1 | Compositions with 2,3-Disubstituted Indoles as Charge Transport Materials, and Display Devices Fabricated Therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2017-12-28 | — | — | US | disclosed |
| WO-2016107459-A1 | COMPOSITIONS WITH 2, 3-DISUBSTITUTED INDOLES AS CHARGE TRANSPORT MATERIALS, AND DISPLAY DEVICES FABRICATED THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170373253-A1 | Compositions with 2,3-Disubstituted Indoles as Charge Transport Materials, and Display Devices Fabricated Therefrom | IDO2, HTR3D, IDO1 | KDM4E 3319/4885ATM 4371/4885L3MBTL1 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.