Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 1.00 |
| ▸ | SHBG | P04278 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 1.00 |
| ▸ | SERPINA6 | P08185 | 6/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 5/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.78 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.78 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cortodoxone SCHEMBL16834876 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL3641463 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL13768127 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL1592553 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL1592718 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL42590 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL24900239 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL14360590 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| Cortodoxone SCHEMBL13352414 | 1.00 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 | |
| SCHEMBL9070396 | 0.91 | HSD17B10 (0.84) | HSD17B10SHBGSMN1; SMN2SERPINA6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2093285-B1 | Method for biocatalysis using filamentous fungi | UNIV THE WEST INDIES (JM) | 2016-07-06 | — | — | EP | disclosed |