Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907051 | 0.95 | PIK3C3 (0.42) | PIK3C3ATMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17907109 | 0.89 | PIK3C3 (0.43) | PIK3C3ATMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17906841 | 0.88 | PIK3C3 (0.40) | PIK3C3ATMPIK3CAPIK3CBRIPK2 | |
| SCHEMBL17906974 | 0.87 | PIK3C3 (0.44) | PIK3C3ATMPIK3CDPIK3R1PIK3CA | |
| SCHEMBL17821069 | 0.87 | ATM (0.47) | PIK3C3ATMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17906711 | 0.87 | PIK3C3 (0.41) | PIK3C3ATMPIK3CAPIK3CBRIPK2 | |
| SCHEMBL17907177 | 0.86 | PIK3C3 (0.43) | PIK3C3ATMPIK3CAPIK3CBRIPK2 | |
| SCHEMBL17819523 | 0.86 | PIK3C3 (0.45) | PIK3C3ATMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17819419 | 0.86 | PIK3C3 (0.40) | PIK3C3ATMPIK3CAPIK3CBRAB9A | |
| SCHEMBL17906982 | 0.86 | PIK3C3 (0.40) | PIK3C3ATMPIK3CAPIK3CBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |