Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627414 | 0.79 | TAAR1 (0.58) | TAAR1MAPK1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL4302387 | 0.79 | CYP2C19 (0.52) | TAAR1MAPK1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL10086475 | 0.77 | TSHR (0.52) | ALDH1A1TSHRCYP2C19KMT2AMEN1 | |
| SCHEMBL5667854 | 0.76 | TAAR1 (0.48) | TAAR1MAPK1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL284909 | 0.76 | TAAR1 (0.48) | TAAR1MAPK1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL8317714 | 0.75 | CYP2C19 (0.46) | TAAR1MAPK1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL9395059 | 0.75 | ESR1 (0.54) | ALDH1A1TSHRKMT2AMEN1ESR1 | |
| SCHEMBL4249887 | 0.74 | TAAR1 (0.46) | TAAR1MAPK1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL7642588 | 0.74 | CYP2C19 (0.46) | TAAR1MAPK1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL460018 | 0.74 | TAAR1 (0.65) | TAAR1MAPK1ALDH1A1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041599-A1 | HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES | Universiteit Twente (NL) | 2016-07-13 | — | — | EP | disclosed |