Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3241793 | 0.97 | TAAR1 (0.62) | TAAR1MAPK1KCNN4CYP2D6CYP1A2 | |
| SCHEMBL2911752 | 0.89 | TAAR1 (0.54) | TAAR1MAPK1CYP3A4KIF11MAPT | |
| SCHEMBL30911317 | 0.82 | KCNA5 (0.47) | TAAR1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30911318 | 0.82 | KCNA5 (0.47) | TAAR1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5221334 | 0.80 | TAAR1 (0.54) | TAAR1KCNN4CYP2D6CYP3A4KIF11 | |
| SCHEMBL323323 | 0.79 | TAAR1 (1.00) | TAAR1MAPK1KCNN4CYP2D6CYP1A2 | |
| SCHEMBL9505717 | 0.79 | TAAR1 (0.65) | TAAR1MAPK1KCNN4CYP2D6CYP1A2 | |
| SCHEMBL10505310 | 0.79 | TAAR1 (0.65) | TAAR1MAPK1KCNN4CYP2D6CYP1A2 | |
| SCHEMBL24726695 | 0.78 | TAAR1 (0.43) | TAAR1MAPK1MAPTALDH1A1 | |
| SCHEMBL77069 | 0.77 | TAAR1 (0.62) | TAAR1MAPK1KCNN4CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| EP-1773768-A4 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2008-08-06 | — | — | EP | claimed |
| US-20070112007-A1 | Cyclohexyl-1, 4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-17 | — | — | US | claimed |
| EP-1773768-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | claimed |
| US-20060074105-A1 | Substituted quinoline and quinazoline inhibitors of quinone reductase 2 | SERENEX, INC. (US) | 2006-04-06 | — | — | US | claimed |
| WO-2006034235-A2 | SUBSTITUTED QUINOLINE AND QUINAZOLINE INHIBITORS OF QUINONE REDUCTASE 2 | SERENEX, INC. (US) | 2006-03-30 | — | — | WO | claimed |
| WO-2006012642-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| US-12398151-B2 | Sumo inhibitor compounds and uses thereof | Suvalent Therapeutics, Inc. (US) | 2025-08-26 | — | — | US | disclosed |
| CN-114040947-B | Cationic electrodeposition coating composition | 日涂汽车涂料有限公司 | 2023-02-28 | — | — | CN | disclosed |
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | CIT THERAPEUTICS LLC | 2022-06-09 | — | — | US | disclosed |
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | CIT THERAPEUTICS LLC | 2022-06-09 | — | — | US | disclosed |
| CN-114040947-A | Cationic electrodeposition coating composition | 日涂汽车涂料有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-4649204-A | ANTIDEPRESSANTS | MCNEILAB, INC. (US) | 1987-03-10 | — | — | US | disclosed |
| US-4548994-A | IMMOBILIZATION ON AFFINITY RESIN | THE UPJOHN COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0057600-B1 | AFFINITY RESINS AND THEIR USE IN ISOLATING BACTERIAL LUCIFERASE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1985-05-08 | — | — | EP | disclosed |
| EP-0139358-A2 | N6-substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |
| US-4412001-A | IMMOBILIZATION BY BINDING TO A LIGAND-SPACER-SUPPORT; WASHING; DESORPTION; PURIFICATION | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0057600-A2 | Affinity resins and their use in isolating bacterial luciferase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1982-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074105-A1 | Substituted quinoline and quinazoline inhibitors of quinone reductase 2 | NQO2, QTRT1, QTRT2 | TAAR1 3707/4885MAPK1 2997/4885KCNN4 3727/4885 |
| US-20070112007-A1 | Cyclohexyl-1, 4-diamine compounds | PKD1, DDC, DPYD | TAAR1 2349/4885MAPK1 1332/4885KCNN4 3955/4885 |
| US-12398151-B2 | Sumo inhibitor compounds and uses thereof | SUMO1, SUMO2, SUMO3 | TAAR1 4690/4885MAPK1 2107/4885KCNN4 4843/4885 |
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | SUMO1, SUMO2, SUMO3 | TAAR1 4690/4885MAPK1 2107/4885KCNN4 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.