Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 16/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17820182 | 0.85 | ROCK2 (0.46) | ROCK2ROCK1PARP14ATMCCR2 | |
| SCHEMBL17907015 | 0.78 | ROCK2 (0.46) | ROCK2ROCK1PARP14ATMCCR2 | |
| SCHEMBL17819472 | 0.77 | ATM (0.46) | ROCK2ROCK1PARP14ATMCCR2 | |
| SCHEMBL17820848 | 0.75 | ROCK2 (0.45) | ROCK2ROCK1PARP14ATMKAT2B | |
| SCHEMBL17819940 | 0.74 | ATM (0.42) | ROCK2ROCK1ATMCCR2PIK3CA | |
| SCHEMBL17819675 | 0.72 | ATM (0.43) | ROCK2ROCK1ATMCCR2PIK3CA | |
| SCHEMBL17819690 | 0.71 | ATM (0.48) | ROCK2ATMKAT2BPIK3CA | |
| SCHEMBL17906787 | 0.70 | ATM (0.45) | ROCK2ATMPIK3CA | |
| SCHEMBL17907171 | 0.70 | PRKDC (0.39) | ATMPIK3CA | |
| SCHEMBL17820572 | 0.70 | ATM (0.43) | ROCK2ROCK1PARP14ATMCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |