Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907303 | 0.78 | DGAT1 (0.59) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17907378 | 0.78 | DGAT1 (0.59) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17907331 | 0.77 | DGAT1 (0.57) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17907344 | 0.70 | DGAT1 (0.56) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16532146 | 0.70 | DGAT1 (0.56) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16532048 | 0.70 | DGAT1 (0.69) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17907315 | 0.69 | DGAT1 (0.57) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17907308 | 0.69 | DGAT1 (0.57) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17907313 | 0.69 | DGAT1 (0.54) | DGAT1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17907299 | 0.69 | DGAT1 (0.60) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042907-A1 | DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Medshine Discovery Inc. (CN) | 2016-07-13 | — | — | EP | disclosed |