Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907386 | 0.90 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL16532070 | 0.79 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL16532026 | 0.78 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL17907361 | 0.78 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL22894551 | 0.75 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL17907297 | 0.74 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL19557931 | 0.73 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL1424724 | 0.73 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL2517282 | 0.73 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL1424300 | 0.73 | DGAT1 (0.59) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042907-A1 | DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Medshine Discovery Inc. (CN) | 2016-07-13 | — | — | EP | disclosed |