Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907496 | 1.00 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL751929 | 0.98 | KDM4E (0.57) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL751930 | 0.98 | KDM4E (0.57) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL752857 | 0.94 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL752858 | 0.94 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL18601432 | 0.89 | KDM4E (0.56) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL18601431 | 0.89 | KDM4E (0.56) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL2840220 | 0.85 | KDM4E (0.59) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL2840222 | 0.85 | KDM4E (0.59) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL2790877 | 0.79 | KDM4E (0.65) | CYSLTR2CYSLTR1KDM4EMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |