Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | PDE5A | O76074 | 7/20 | 0.57 |
| ▸ | GUCY1A1 | Q02108 | 11/20 | 0.54 |
| ▸ | GUCY1B1 | Q02153 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30507540 | 0.89 | ADORA3 (0.82) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL174915 | 0.89 | ADORA3 (0.82) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL18496418 | 0.88 | ADORA3 (0.81) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL6222071 | 0.86 | ADORA3 (0.68) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| Dimethyl Sulfoxide SCHEMBL1931525 | 0.85 | ADORA3 (0.76) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL174772 | 0.83 | ADORA3 (0.69) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL15111729 | 0.83 | ADORA3 (0.62) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL18212216 | 0.83 | ADORA3 (0.82) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL16244578 | 0.83 | ADORA3 (0.61) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL16458523 | 0.83 | ADORA3 (0.63) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802580-B1 | SUBSTITUTED TRIAZINE DERIVATIVES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | BAYER IP GMBH (DE) | 2016-07-13 | — | — | EP | disclosed |