Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 15/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17907587 | 0.94 | ENPP2 (0.58) | ENPP2PTGDR2P2RY1CHRM4 | |
| SCHEMBL17907702 | 0.92 | ENPP2 (0.74) | ENPP2PTGDR2P2RY1DRD2DRD4 | |
| SCHEMBL17907705 | 0.90 | ENPP2 (0.62) | ENPP2PTGDR2P2RY1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL17907629 | 0.90 | ENPP2 (0.51) | ENPP2PTGDR2 | |
| Hydrochloric Acid SCHEMBL17907617 | 0.90 | ENPP2 (0.51) | ENPP2PTGDR2 | |
| SCHEMBL14891001 | 0.86 | ENPP2 (0.49) | ENPP2PTGDR2 | |
| Hydrochloric Acid SCHEMBL14890995 | 0.86 | ENPP2 (0.49) | ENPP2PTGDR2 | |
| Hydrochloric Acid SCHEMBL17907592 | 0.85 | ENPP2 (0.82) | ENPP2 | |
| SCHEMBL15418109 | 0.82 | ENPP2 (0.61) | ENPP2 | |
| SCHEMBL15418033 | 0.82 | ENPP2 (0.61) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687531-B1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2016-07-13 | — | — | EP | disclosed |