SCHEMBL17907607

SCHEMBL17907607

Cc1nc(-c2ccccc2)sc1Cn1c2c(c3cccnc31)CCN(C(=O)COCC(C)(C)C(=O)O)C2

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17907684 0.88 ENPP2 (0.68) ENPP2
SCHEMBL17907651 0.85 ENPP2 (0.55) ENPP2
SCHEMBL12697550 0.83 ENPP2 (0.60) ENPP2
SCHEMBL17907853 0.83 ENPP2 (0.55) ENPP2
SCHEMBL14890906 0.82 ENPP2 (0.64) ENPP2
SCHEMBL17907723 0.82 ENPP2 (0.53) ENPP2
SCHEMBL14892301 0.82 ENPP2 (0.57) ENPP2
SCHEMBL17907659 0.82 ENPP2 (0.67) ENPP2
SCHEMBL17907823 0.82 ENPP2 (0.60) ENPP2
SCHEMBL17907637 0.82 ENPP2 (0.60) ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687531-B1 TETRAHYDROCARBOLINE DERIVATIVE ONO PHARMACEUTICAL CO (JP) 2016-07-13 EP claimed