SCHEMBL17907712

SCHEMBL17907712

O=C(COc1cc[c]cc1)N1CCc2c(n(Cc3ccc(Oc4ccccc4)cc3)c3ncccc23)C1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12697430 0.92 ENPP2 (0.65) ENPP2
SCHEMBL17907823 0.85 ENPP2 (0.60) ENPP2
SCHEMBL17907791 0.82 ENPP2 (0.81) ENPP2
SCHEMBL17907771 0.82 ENPP2 (0.61) ENPP2
SCHEMBL17907703 0.81 ENPP2 (0.82) ENPP2
SCHEMBL17907689 0.81 ENPP2 (0.73) ENPP2
SCHEMBL17907773 0.81 ENPP2 (0.59) ENPP2
SCHEMBL17907786 0.80 ENPP2 (0.76) ENPP2
SCHEMBL17907687 0.80 ENPP2 (0.68) ENPP2
SCHEMBL17907792 0.80 ENPP2 (0.65) ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687531-B1 TETRAHYDROCARBOLINE DERIVATIVE ONO PHARMACEUTICAL CO (JP) 2016-07-13 EP claimed