SCHEMBL179204

SCHEMBL179204

c1cc2ccc1CNCCNCCNCc1ccc(cc1)CNCCNCCNC2

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.64
TERT O14746 2/20 0.54
HIF1A Q16665 1/20 0.40
MAPT P10636 1/20 0.40
PDE4A P27815 1/20 0.40
KDR P35968 1/20 0.40
PNMT P11086 4/20 0.36
CD44 P16070 1/20 0.36
MAOB P27338 1/20 0.36
HTR2C P28335 1/20 0.35
CXCR4 P61073 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SOD3 P08294 1/20 0.31
CHKA P35790 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13830412 0.88 APEX1 (0.52) APEX1TERTPNMTCD44MAOB
SCHEMBL14878447 0.83 APEX1 (0.48) APEX1TERTPNMTCD44MAOB
SCHEMBL12974674 0.79 APEX1 (0.45) APEX1TERTCXCR4SMN1; SMN2ADRA2C
SCHEMBL15256449 0.78 APEX1 (0.44) APEX1TERT
SCHEMBL15267824 0.78 APEX1 (0.44) APEX1TERT
SCHEMBL30050918 0.77 APEX1 (0.60) APEX1TERTPNMTCD44MAOB
SCHEMBL18128899 0.77 APEX1 (0.60) APEX1TERTPNMTCD44MAOB
SCHEMBL29386754 0.77 APEX1 (0.60) APEX1TERTPNMTCD44MAOB
SCHEMBL1103773 0.77 APEX1 (0.43) APEX1TERTHTR2CCXCR4
SCHEMBL22210744 0.76 APEX1 (0.52) APEX1TERTHIF1AMAPTPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134667-A1 APPARATUS FOR MEASURING ANALYTES USING FET ARRAYS Life Technologies Corporation (US) 2023-02-15 EP disclosed
US-20210116414-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES Life Technologies Corporation (US) 2021-04-22 US disclosed
US-9927393-B2 Methods and apparatus for measuring analytes Life Technologies Corporation (US) 2018-03-27 US disclosed
EP-2982437-B1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS LIFE TECHNOLOGIES CORP (US) 2017-12-06 EP disclosed
US-20170194985-A1 METHODS AND COMPUTER PROGRAM PRODUCTS FOR COMPRESSION OF SEQUENCING DATA Life Technologies Corporation 2017-07-06 US disclosed
US-9515676-B2 Methods and computer program products for compression of sequencing data Life Technologies Corporation (US) 2016-12-06 US disclosed
US-9458502-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2016-10-04 US disclosed
US-9269708-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2016-02-23 US disclosed
US-9194000-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2015-11-24 US disclosed
EP-2762872-B1 Methods and apparatus for measuring analytes using large scale FET arrays LIFE TECHNOLOGIES CORP (US) 2015-09-16 EP disclosed
US-20110241081-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-06 US disclosed
US-20110230375-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-09-22 US disclosed
US-20110217697-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (CA) 2011-09-08 US disclosed
US-7948015-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2011-05-24 US disclosed
US-20100301398-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES ION TORRENT SYSTEMS INCORPORATED (US) 2010-12-02 US disclosed
US-20100197507-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS ION TORRENT SYSTEMS INCORPORATED (US) 2010-08-05 US disclosed
US-20100188073-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS ION TORRENT SYSTEMS INCORPORATED (US) 2010-07-29 US disclosed
US-20100137143-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES ION TORRENT SYSTEMS INCORPORATED (US) 2010-06-03 US disclosed
US-20090127589-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-05-21 US disclosed
US-20090026082-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-01-29 US disclosed