Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | TERT | O14746 | 2/20 | 0.52 |
| ▸ | CHKA | P35790 | 3/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | CD44 | P16070 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18128899 | 1.00 | APEX1 (0.60) | APEX1TERTCHKAPNMTCD44 | |
| SCHEMBL30050918 | 1.00 | APEX1 (0.60) | APEX1TERTCHKAPNMTCD44 | |
| SCHEMBL21955684 | 0.86 | APEX1 (0.42) | APEX1TERTCHKA | |
| SCHEMBL19089065 | 0.86 | APEX1 (0.42) | APEX1TERTCHKA | |
| SCHEMBL4359812 | 0.86 | — | — | |
| SCHEMBL22210744 | 0.80 | APEX1 (0.52) | APEX1TERTPNMTCD44MAOB | |
| SCHEMBL6515380 | 0.80 | APEX1 (0.45) | APEX1TERTCHKAPNMTCD44 | |
| SCHEMBL4946987 | 0.79 | CHKA (0.38) | APEX1TERTCHKA | |
| SCHEMBL9566479 | 0.78 | ACHE (0.43) | APEX1TERTPNMTCD44MAOB | |
| SCHEMBL27018293 | 0.78 | HTR2C (0.41) | APEX1TERTHTR2CADRB1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022029218-A1 | METHOD FOR DATA FUSION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-02-10 | — | — | WO | disclosed |