Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17921627 | 1.00 | TSHR (0.45) | TSHRLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL17908862 | 0.84 | TSHR (0.50) | TSHRLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL17909307 | 0.84 | TSHR (0.50) | TSHRLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL17908940 | 0.84 | TSHR (0.50) | TSHRLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL17921629 | 0.81 | MAPT (0.41) | TSHRLMNAALDH1A1MAPTCYP3A4 | |
| SCHEMBL17921626 | 0.81 | MAPT (0.41) | TSHRLMNAALDH1A1MAPTCYP3A4 | |
| SCHEMBL14179962 | 0.80 | TSHR (0.45) | TSHRLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL4430084 | 0.80 | TSHR (0.70) | TSHRLMNAALDH1A1MAPTHSD17B10 | |
| SCHEMBL20725788 | 0.79 | CYP1A2 (0.31) | MAPTCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL17909574 | 0.78 | CYP3A4 (0.56) | TSHRLMNAALDH1A1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200998-A1 | ETHER-CONTAINING MONOESTER COMPOUND AND USE THEREOF | MORESCO CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200998-A1 | ETHER-CONTAINING MONOESTER COMPOUND AND USE THEREOF | SFN, CCNE2, MSMO1 | TSHR 4877/4885LMNA 3960/4885ALDH1A1 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.