Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17923675 | 0.94 | PDK2 (0.44) | PDK2MAPK1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL22797311 | 0.92 | MAPK1 (0.45) | PDK2MAPK1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL26369373 | 0.92 | MAPK1 (0.45) | PDK2MAPK1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL5763937 | 0.87 | PDK2 (0.46) | PDK2MAPK1ALDH1A1PTGDR2KDM4E | |
| SCHEMBL12469930 | 0.86 | PDK2 (0.49) | PDK2MAPK1KDM4ELMNAMAPT | |
| SCHEMBL31396643 | 0.86 | PDK2 (0.49) | PDK2MAPK1KDM4ELMNAMAPT | |
| SCHEMBL29603046 | 0.86 | PDK2 (0.49) | PDK2MAPK1KDM4ELMNAMAPT | |
| SCHEMBL45620 | 0.86 | PDK2 (0.49) | PDK2MAPK1KDM4ELMNAMAPT | |
| SCHEMBL16628918 | 0.86 | PDK2 (0.49) | PDK2MAPK1KDM4ELMNAMAPT | |
| SCHEMBL31396648 | 0.86 | PDK2 (0.49) | PDK2MAPK1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160211456-A1 | PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF | LUMINESCENCE TECHNOLOGY CORP. | 2016-07-21 | — | — | US | disclosed |
| US-20160211456-A1 | PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF | LUMINESCENCE TECHNOLOGY CORP. | 2016-07-21 | — | — | US | disclosed |
| US-20160211456-A1 | PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF | LUMINESCENCE TECHNOLOGY CORP. | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160211456-A1 | PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF | POP1, TERB1, AP2B1 | PDK2 2688/4885MAPK1 2317/4885ALDH1A1 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.