AP2B1

AP-2 complex subunit beta · P63010 · AP2B1 on Sugi Atlas →

0 patent compounds predicted against AP2B1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AP2B1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Mechanisms of Lipodystrophy in HIV-Infected Pateints PHASE4COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD PHASE3COMPLETED
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes PHASE2RECRUITING
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
ASTX727 and Nivolumab in Squamous Cell Carcinoma of the Head and Neck PHASE1WITHDRAWN
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Choline Effects - Pre-symptomatic AD PHASE1COMPLETED
Acute Effect of HP-211 (Axulin) on Blood Glucose and Serum Insulin Responses in Healthy Lean and Overweight Humans PHASE1COMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport? nanUNKNOWN
Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients nanRECRUITING
Transcriptomic Analysis to Put an End to Misdiagnosis in Patients With Rare Muscle Diseases nanRECRUITING
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure nanUNKNOWN
High Altitude Medical Research Expedition Himlung 2013 - a Study of Human Adaption to Hypoxia nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study nanCOMPLETED
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry Bad Cholesterol in the Blood nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Novel Biomarkers in Inflammatory Bowel Disease nanCOMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts nanCOMPLETED
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract nanUNKNOWN
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED
Effect of Exercise on the Human Skeletal Muscle Phosphoproteome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a AP2B1 binder may also engage these)

ProteinNameSimilarity
Q08DS7 1.000 Q08DS7 →
P62944 1.000 P62944 →
P63009 1.000 P63009 →
Q9DBG3 1.000 Q9DBG3 →
O35643 0.998 O35643 →
Q10567 0.996 Q10567 →
P52303 0.995 P52303 →
Q9LDK9 0.986 Q9LDK9 →
Q6DDM4 0.985 Q6DDM4 →
A4L9P7 0.985 A4L9P7 →
Q9SUS3 0.984 Q9SUS3 →
O81742 0.984 O81742 →
F4IDS7 0.984 F4IDS7 →
A7MBJ5 0.983 A7MBJ5 →
P42346 0.982 P42346 →
Q6TRW4 0.981 Q6TRW4 →
COPG1 Coatomer subunit gamma-1 0.981 landscape →
Q13367 0.981 Q13367 →
Q9BPX3 0.981 Q9BPX3 →
Q29G21 0.981 Q29G21 →
Q9WV76 0.981 Q9WV76 →
P53620 0.980 P53620 →
PLAA Phospholipase A-2-activating protein 0.980 landscape →
Q9Z1T1 0.980 Q9Z1T1 →
ECPAS Proteasome adapter and scaffold protein ECM29 0.980 landscape →
Q9I8E6 0.980 Q9I8E6 →
Q5F3U9 0.980 Q5F3U9 →
IPO7 Importin-7 0.980 landscape →
PDS5A Sister chromatid cohesion protein PDS5 homolog A 0.979 landscape →
Q7YRF1 0.979 Q7YRF1 →