Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17930321 | 0.93 | ROCK2 (0.42) | ROCK2 | |
| SCHEMBL31384427 | 0.83 | ROCK2 (0.52) | ROCK2 | |
| SCHEMBL675878 | 0.83 | ROCK2 (0.52) | ROCK2 | |
| SCHEMBL29923955 | 0.82 | ROCK2 (0.45) | ROCK2 | |
| SCHEMBL254071 | 0.81 | ROCK2 (0.53) | ROCK2 | |
| Hydrochloric Acid SCHEMBL29941928 | 0.80 | ROCK2 (0.52) | ROCK2 | |
| SCHEMBL16046651 | 0.80 | ROCK2 (0.52) | ROCK2 | |
| SCHEMBL28039785 | 0.79 | ROCK2 (0.52) | ROCK2 | |
| SCHEMBL17924637 | 0.79 | CA1 (0.33) | — | |
| SCHEMBL19469296 | 0.78 | ROCK2 (0.50) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-05 | — | — | US | disclosed |
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | ROCK2 1715/4885 |
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | ROCK2 1715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.