Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17927238 | 1.00 | NR1I2 (0.43) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL17927190 | 0.89 | NR1I2 (0.45) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL17927192 | 0.89 | NR1I2 (0.45) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL20366995 | 0.89 | NR1I2 (0.45) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL17927200 | 0.89 | NR1I2 (0.43) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL17927201 | 0.89 | NR1I2 (0.43) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL17927279 | 0.89 | NR1I2 (0.43) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL17927277 | 0.89 | NR1I2 (0.43) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL20360585 | 0.89 | CYP3A4 (0.43) | NR1I2OPRK1KARS1RXRACCNE1 | |
| SCHEMBL20360586 | 0.89 | CYP3A4 (0.43) | NR1I2OPRK1KARS1RXRACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245184-A1 | DEHYDROABIETIC ACID (DHAA) DERIVATIVES FOR USE AS ION CHANNEL OPENERS | Elinder, Fredrik (SE) | 2017-11-22 | — | — | EP | claimed |
| WO-2016114707-A1 | DEHYDROABIETIC ACID (DHAA) DERIVATIVES FOR USE AS ION CHANNEL OPENERS | ELINDER FREDRIK (SE) | 2016-07-21 | — | — | WO | claimed |
| EP-3245184-A1 | DEHYDROABIETIC ACID (DHAA) DERIVATIVES FOR USE AS ION CHANNEL OPENERS | Elinder, Fredrik (SE) | 2017-11-22 | — | — | EP | disclosed |
| WO-2016114707-A1 | DEHYDROABIETIC ACID (DHAA) DERIVATIVES FOR USE AS ION CHANNEL OPENERS | ELINDER FREDRIK (SE) | 2016-07-21 | — | — | WO | disclosed |