Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 4/20 | 0.40 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20359899 | 1.00 | CYP3A4 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL20360586 | 1.00 | CYP3A4 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927254 | 0.89 | NR1I2 (0.45) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927255 | 0.89 | NR1I2 (0.45) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927279 | 0.89 | NR1I2 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927200 | 0.89 | NR1I2 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927238 | 0.89 | NR1I2 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927201 | 0.89 | NR1I2 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927239 | 0.89 | NR1I2 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 | |
| SCHEMBL17927277 | 0.89 | NR1I2 (0.43) | CYP3A4MAPTALDH1A1ALOX15NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180193294-A1 | Dehydroabietic acid (DHAA) derivatives for use as ion channel openers | ELINDER FREDRIK (SE) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180193294-A1 | Dehydroabietic acid (DHAA) derivatives for use as ion channel openers | KCNAB1, KCNA1, KCNE1 | CYP3A4 2080/4885MAPT 4019/4885ALDH1A1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.