⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4871761 | 0.97 | KCNN4 (0.35) | — | |
| SCHEMBL15999961 | 0.83 | KCNN4 (0.36) | — | |
| SCHEMBL30203104 | 0.82 | — | — | |
| SCHEMBL7828005 | 0.79 | KCNN4 (0.34) | — | |
| SCHEMBL3372959 | 0.79 | — | — | |
| SCHEMBL23689890 | 0.79 | — | — | |
| SCHEMBL12349925 | 0.79 | KCNN4 (0.34) | — | |
| SCHEMBL3971146 | 0.79 | — | — | |
| SCHEMBL15198095 | 0.75 | KCNN4 (0.33) | — | |
| SCHEMBL12115800 | 0.75 | KCNN4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | claimed |
| CN-109456200-B | Preparation method of m-xylylenediamine | 万华化学集团股份有限公司 | 2021-07-23 | — | — | CN | claimed |
| EP-2614065-A1 | SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2013-07-17 | — | — | EP | claimed |
| WO-2012080990-A1 | SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-06-21 | — | — | WO | claimed |
| US-20100160324-A1 | PYRAZOLE DERIVATIVES AS THAT MODULATE THE ACTIVITY OF CDK, GSK AND AURORA KINASES | ASTEX THERAPEUTICS LIMITED (GB) | 2010-06-24 | — | — | US | claimed |
| EP-1836188-A1 | PYRAZOLE DERIVATIVES AS THAT MODULATE THE ACTIVITY OF CDK, GSK AND AURORA KINASES | Astex Therapeutics Limited (GB) | 2007-09-26 | — | — | EP | claimed |
| WO-2006070198-A1 | PYRAZOLE DERIVATIVES AS THAT MODULATE THE ACTIVITY OF CDK, GSK AND AURORA KINASES | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-06 | — | — | WO | claimed |
| WO-2002012161-A1 | PROCESS FOR THE CARBONYLATION OF OXIRANES | DAVY PROCESS TECHNOLOGY LIMITED (GB) | 2002-02-14 | — | — | WO | claimed |
| EP-1179524-A1 | Process for the carbonylation of oxiranes | Kvaerner Process Technology Limited (GB) | 2002-02-13 | — | — | EP | claimed |
| EP-0286279-A1 | Synthesis of substituted pyrazoles | ELI LILLY AND COMPANY (US) | 1988-10-12 | — | — | EP | claimed |
| US-12624018-B1 | Inhibitors of RIPK2 and medical uses thereof | ODYSSEY THERAPEUTICS, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260116859-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20250263408-A1 | SPLEEN TYROSINE KINASE INHIBITORS | UNIQUEST PTY LTD (AU) | 2025-08-21 | — | — | US | disclosed |
| CN-119965352-A | Application of trifluoromethyl pyrazolyl dimethyl phosphonate isomer compound in electrolyte, electrolyte additive and lithium ion battery electrolyte | 华鼎国联动力电池有限公司 | 2025-05-09 | — | — | CN | disclosed |
| US-20250049776-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR A SYSTEMIC TREATMENT OF DISEASES AND CONDITIONS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (FR) | 2025-02-13 | — | — | US | disclosed |
| EP-0412849-B1 | Azole pesticides | AGREVO UK LTD (GB) | 1995-12-20 | — | — | EP | disclosed |
| EP-0412849-A2 | Azole pesticides | AgrEvo UK Limited (GB) | 1991-02-13 | — | — | EP | disclosed |
| US-4820845-A | Alkylation of 3(5)-cyano-1H-pyrazole-4-carboxylic acid esters | ELI LILLY AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0286279-A1 | Synthesis of substituted pyrazoles | ELI LILLY AND COMPANY (US) | 1988-10-12 | — | — | EP | disclosed |
| EP-0139182-A2 | Herbicidal agents containing a photosynthesis inhibitor herbicide together with 1,4-disubstituted pyrazole derivatives | BAYER AG (DE) | 1985-05-02 | — | — | EP | disclosed |