⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22924802 | 0.79 | — | — | |
| SCHEMBL15999961 | 0.79 | KCNN4 (0.36) | — | |
| SCHEMBL179276 | 0.79 | — | — | |
| SCHEMBL2646308 | 0.78 | KCNN4 (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL4871761 | 0.77 | KCNN4 (0.35) | — | |
| SCHEMBL23689890 | 0.75 | — | — | |
| SCHEMBL7828005 | 0.75 | KCNN4 (0.34) | — | |
| SCHEMBL12349925 | 0.75 | KCNN4 (0.34) | — | |
| SCHEMBL3971146 | 0.75 | — | — | |
| SCHEMBL11170967 | 0.75 | KCNN4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237534-B | A kind of pyrazolo pyridine derivatives and its preparation method and application | 山西大学 | 2016-11-30 | — | — | CN | claimed |
| CN-105237534-A | Pyrazolopyridine derivative and preparation method and application thereof | UNIV SHANXI | 2016-01-13 | — | — | CN | claimed |
| EP-1446092-B1 | USE OF CAPRYLOYL GLUTAMATE SALTS AND CAPRYLOYL HYDROLYSATE SALTS OF WHEAT AND/OR RICE PROTEIN IN DETERGENT AND COSMETIC COMPOSITIONS | ZSCHIMMER & SCHWARZ ITALIANA S (IT) | 2008-08-13 | — | — | EP | claimed |
| EP-1074247-B1 | Use of zinc alkylsulphates and/or alky(poly)ethoxysulphates as surfactants and preservatives in cleansing or cosmetic compositions | ZSCHIMMER & SCHWARZ ITALIANA S (IT) | 2006-09-27 | — | — | EP | claimed |
| EP-0757518-B1 | SYNERGISTIC WATER SOLUBLE PRESERVATIVE COMPOSITIONS OF BIOCIDAL MIXTURES | ISP CHEMICALS INC (US) | 2001-05-30 | — | — | EP | claimed |
| CN-114206300-A | Preventing and reducing keratinization disorder and related cosmetic | 默克专利股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114173727-A | Antimicrobial device for insertion needle | 3M创新有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-107205387-B | Powder formulations comprising insect repellent | 默克专利股份有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-107635589-B | Essentially antimicrobial porous matrix composites and methods of making the same | 约翰·保罗·威尔逊 | 2020-07-17 | — | — | CN | disclosed |
| CN-105237534-B | A kind of pyrazolo pyridine derivatives and its preparation method and application | 山西大学 | 2016-11-30 | — | — | CN | disclosed |
| CN-105237534-A | Pyrazolopyridine derivative and preparation method and application thereof | UNIV SHANXI | 2016-01-13 | — | — | CN | disclosed |
| EP-1781635-B1 | POTASSIUM CHANNEL INHIBITORS | MERCK SHARP & DOHME (US) | 2012-06-13 | — | — | EP | disclosed |
| US-6287584-B1 | Flexible hydrophilic articles especially sponges, having a residual antimicrobial effect | RECKITT & COLMAN INC. | 2001-09-11 | — | — | US | disclosed |
| WO-2001032138-A1 | ANTIMICROBIAL WIPING ARTICLE | JEYES GROUP LIMITED (GB) | 2001-05-10 | — | — | WO | disclosed |
| US-6228389-B1 | SPONGE | RECKITT BENCKISER INC. | 2001-05-08 | — | — | US | disclosed |
| EP-0959683-A1 | SYNERGISTIC ANTIMICROBIAL COMPOSITIONS CONTAINING 1-HYDROXYMETHYLPYRAZOLE AND A PRESERVATIVE | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5859040-A | CONTROLLING GROWTH OF BACTERIA AND/OR FUNGI | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0869216-A1 | Flexible hydrophilic articles having a durable antimicrobial effect | Reckitt & Colman Inc. (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5661149-A | Synergistic antimicrobial compositions containing 1-hydroxymethylpyrazole and a preservative | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1997024031-A1 | SYNERGISTIC ANTIMICROBIAL COMPOSITIONS CONTAINING 1-HYDROXYMETHYLPYRAZOLE AND A PRESERVATIVE | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-07-10 | — | — | WO | disclosed |