Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17936284 | 0.87 | HSD17B10 (0.41) | HSD17B10 | |
| SCHEMBL17933350 | 0.78 | GRM8 (0.30) | — | |
| SCHEMBL17933371 | 0.78 | GRM8 (0.30) | — | |
| SCHEMBL17933352 | 0.77 | PTPRC (0.31) | HSD17B10 | |
| SCHEMBL17933341 | 0.75 | — | — | |
| SCHEMBL17059084 | 0.73 | HSD17B10 (0.35) | HSD17B10 | |
| SCHEMBL17933339 | 0.73 | PTPRC (0.31) | HSD17B10 | |
| SCHEMBL17933353 | 0.71 | CYP1A2 (0.36) | HSD17B10 | |
| SCHEMBL17933342 | 0.71 | PTPRC (0.30) | — | |
| SCHEMBL17936294 | 0.65 | SLC7A5 (0.39) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | HSD17B10 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.