Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.73 |
| ▸ | MT-CO2 | P00403 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934374 | 0.90 | MYC (0.59) | MYCMT-CO2KMT2AMEN1MAPK1 | |
| SCHEMBL17934018 | 0.85 | MYC (0.54) | MYCMT-CO2KMT2AMEN1MAPK1 | |
| SCHEMBL17927359 | 0.84 | MYC (1.00) | MYCKMT2AMEN1L3MBTL1PADI4 | |
| SCHEMBL17934014 | 0.84 | MYC (0.53) | MYCMT-CO2KMT2AMEN1MAPK1 | |
| SCHEMBL17934013 | 0.82 | MYC (0.52) | MYCMT-CO2KMT2AMEN1MAPK1 | |
| SCHEMBL17927384 | 0.73 | MYC (0.82) | MYCKMT2AMEN1L3MBTL1 | |
| SCHEMBL17927374 | 0.71 | MYC (0.77) | MYCKMT2AMEN1L3MBTL1 | |
| SCHEMBL17934468 | 0.70 | MYC (0.76) | MYCKMT2AMEN1L3MBTL1 | |
| SCHEMBL26266093 | 0.69 | MYC (0.75) | MYCMT-CO2KMT2AMEN1L3MBTL1 | |
| SCHEMBL17934016 | 0.69 | MYC (0.75) | MYCMT-CO2KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |