Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934018 | 0.86 | MYC (0.54) | MYCAPEX1LMNAHPGDMT-CO2 | |
| SCHEMBL17934013 | 0.86 | MYC (0.52) | MYCPOLBLMNAMT-CO2MEN1 | |
| SCHEMBL17934372 | 0.84 | MYC (0.73) | MYCMAPTMT-CO2MEN1KMT2A | |
| SCHEMBL17934374 | 0.84 | MYC (0.59) | MYCMAPTAPEX1MT-CO2MEN1 | |
| SCHEMBL17934017 | 0.79 | MYC (0.72) | MYCPOLBHPGDMEN1KMT2A | |
| SCHEMBL26266093 | 0.73 | MYC (0.75) | MYCPOLBMT-CO2MEN1KMT2A | |
| SCHEMBL17934468 | 0.72 | MYC (0.76) | MYCPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL17934016 | 0.71 | MYC (0.75) | MYCPOLBMT-CO2MEN1KMT2A | |
| SCHEMBL17927359 | 0.70 | MYC (1.00) | MYCPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL17934015 | 0.70 | MYC (0.71) | MYCPOLBMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |