Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17073831 | 0.87 | MAPT (0.54) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL29022659 | 0.86 | PTGES (0.68) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL30504802 | 0.86 | PTGES (0.68) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL29809563 | 0.84 | KDM4E (0.65) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL17019 | 0.84 | KDM4E (0.65) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL1457131 | 0.84 | MAPT (0.51) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL28471046 | 0.84 | MAPT (0.65) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL2870865 | 0.84 | MAPT (0.65) | MAPTALDH1A1HPGDKMT2ANPSR1 | |
| Methyl Alcohol SCHEMBL28904252 | 0.83 | KDM4E (0.64) | MAPTKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL21218517 | 0.83 | PTGES (0.76) | MAPTALDH1A1PTGESMAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318562-A2 | BENZYLBENZENE DERIVATIVES AND METHODS OF USE | Theracos Sub, LLC (US) | 2018-05-09 | — | — | EP | disclosed |
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |