Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.38 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.38 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.37 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18241589 | 0.97 | PTPN1 (0.46) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL17943867 | 0.91 | PTPN1 (0.41) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL2511080 | 0.90 | PTPN1 (0.49) | PTPN1PTPN2PTPN11LGALS3NT5E | |
| SCHEMBL11369527 | 0.89 | PTPN1 (0.39) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL11378816 | 0.88 | TYMP (0.43) | PTPN1LGALS3LGALS4LGALS9LGALS1 | |
| SCHEMBL9393500 | 0.85 | TSHR (0.50) | MAPK1 | |
| SCHEMBL18343982 | 0.85 | TSHR (0.50) | MAPK1 | |
| SCHEMBL1521371 | 0.85 | PTPN1 (0.52) | PTPN1PTPN2PTPN11ANTXR2TMPRSS2 | |
| SCHEMBL4294666 | 0.85 | PTPN1 (0.52) | PTPN1PTPN2PTPN11ANTXR2TMPRSS2 | |
| SCHEMBL20745419 | 0.83 | SSTR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215070-A1 | MICRO CHIRAL REGULATION CELLULOSE CHROMATOGRAPHY STATIONARY PHASE, PREPARATION METHOD AND USE THEREOF | THE FOURTH MILITARY MEDICAL UNIVERSITY (CN) | 2016-07-28 | — | — | US | disclosed |