Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.49 |
| ▸ | ANTXR2 | P58335 | 3/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18241589 | 0.93 | PTPN1 (0.46) | PTPN1ANTXR2F11USP2TMPRSS2 | |
| SCHEMBL17944054 | 0.90 | PTPN1 (0.45) | PTPN1ANTXR2USP2TMPRSS2PDE5A | |
| SCHEMBL8574780 | 0.89 | LGALS9 (0.44) | PTPN1ANTXR2USP2TMPRSS2PDE5A | |
| SCHEMBL8576918 | 0.89 | LGALS9 (0.44) | PTPN1ANTXR2USP2TMPRSS2PDE5A | |
| SCHEMBL8574777 | 0.89 | LGALS9 (0.44) | PTPN1ANTXR2USP2TMPRSS2PDE5A | |
| SCHEMBL17241441 | 0.88 | PTPN1 (0.40) | PTPN1ANTXR2F11USP2TMPRSS2 | |
| SCHEMBL17241440 | 0.88 | PTPN1 (0.40) | PTPN1ANTXR2F11USP2TMPRSS2 | |
| SCHEMBL8575225 | 0.85 | PTPN1 (0.41) | PTPN1ANTXR2USP2TMPRSS2PDE5A | |
| SCHEMBL8576383 | 0.85 | PTPN1 (0.41) | PTPN1ANTXR2USP2TMPRSS2PDE5A | |
| SCHEMBL8577792 | 0.85 | PTPN1 (0.41) | PTPN1ANTXR2USP2TMPRSS2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205616-B1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LTD (AU) | 2016-04-27 | — | — | EP | disclosed |
| CN-104666318-A | Novel sulfated oligosaccharide derivatives | PROGEN PHARMACEUTICALS LTD | 2015-06-03 | — | — | CN | disclosed |
| US-20110245196-A1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PG500 SERIES PTY LTD (AU) | 2011-10-06 | — | — | US | disclosed |
| EP-2205616-A1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | Progen Pharmaceuticals Limited (AU) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009049370-A1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LIMITED (AU) | 2009-04-23 | — | — | WO | disclosed |